Friday, March 26, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 4:30pm | Baseball - Butler vs Knoch | |
| 4:45pm | Baseball - Armstrong vs Freeport | |
| 4:45pm | Softball - Armstrong vs Freeport | |
| 4:45pm | Softball - Mars vs Deer Lakes | |
| 5:00pm | Baseball - Central Catholic @ Penn Hills | |
| 5:00pm | Baseball - Seneca Valley vs Fox Chapel | |
| 5:00pm | Baseball - Peters Township vs Chartiers Valley | |
| 5:00pm | Baseball - Upper St. Clair vs Hampton | |
| 5:00pm | Baseball - Franklin Regional vs Hempfield | |
| 5:00pm | Baseball - North Hills vs Thomas Jefferson | |
| 5:00pm | Softball - Peters Township vs Keystone Oaks | |
| 5:00pm | Softball - Bethel Park vs Shaler | |
| 5:00pm | Softball - Upper St. Clair vs South Allegheny | |
| 5:00pm | Softball - Butler vs New Castle | |
| 5:00pm | Softball - Connellsville vs Hempfield | |
| 5:00pm | Softball - Thomas Jefferson @ Moon | |
| 5:00pm | Baseball - South Fayette vs North Catholic | |
| 5:00pm | Softball - South Fayette @ North Catholic | |
| 6:00pm | Baseball - Woodland Hills vs Carrick | |
| 6:00pm | Softball - Plum @ Fox Chapel | |
| 7:00pm | Girls Basketball - North Allegheny vs Spring-Ford |
# denotes a conference game