Thursday, April 8, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 5:00pm | Baseball - North Hills @ Fox Chapel | |
| 5:00pm | Softball - Norwin vs Butler # | |
| 5:00pm | Softball - North Hills vs Mars # | |
| 5:00pm | Softball - Albert Gallatin vs Laurel Highlands | |
| 5:00pm | Softball - West Allegheny vs Montour | |
| 5:00pm | Softball - Penn-Trafford @ Yough | |
| 5:15pm | Baseball - Chartiers Valley vs Carrick | |
| 5:45pm | Softball - South Fayette vs Trinity # | |
| 7:00pm | Softball - Canon-McMillan @ Latrobe |
# denotes a conference game