Wednesday, September 15, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 3:15pm | Boys Soccer - Fox Chapel vs Seneca Valley # | |
| 7:00pm | Boys Soccer - North Hills vs Carlynton | |
| 7:00pm | Girls Volleyball - Norwin @ Southmoreland | |
| 7:30pm | Boys Soccer - Butler @ North Allegheny # | |
| 7:30pm | Boys Soccer - Pine-Richland vs Shaler # | |
| 7:30pm | Boys Soccer - Connellsville @ Norwin # | |
| 7:30pm | Girls Volleyball - Shaler vs Fox Chapel # | |
| 7:45pm | Girls Soccer - Bethel Park @ Peters Township # | |
| 8:00pm | Girls Soccer - Baldwin @ Upper St. Clair # | |
| 8:00pm | Girls Soccer - Canon-McMillan vs Moon # |
# denotes a conference game