Monday, October 25, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 6:30pm | Girls Soccer - Bethel Park vs Fox Chapel | |
| 6:30pm | Girls Soccer - Seneca Valley vs Penn-Trafford | |
| 6:30pm | Girls Soccer - Norwin vs North Hills | |
| 6:30pm | Girls Soccer - Butler vs Mt. Lebanon | |
| 6:30pm | Girls Soccer - Peters Township vs Pine-Richland |
# denotes a conference game