Tuesday, December 28, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 11:00am | Girls Basketball - Franklin Regional vs Greensburg Central Catholic | |
| 12:45pm | Girls Basketball - Albert Gallatin vs Chartiers-Houston | |
| 1:00pm | Boys Basketball - Upper St. Clair vs Franklin Regional | |
| 1:30pm | Girls Basketball - North Allegheny vs North Catholic | |
| 2:00pm | Girls Basketball - North Hills vs Seton LaSalle | |
| 2:30pm | Boys Basketball - Bethel Park vs Shaler | |
| 3:00pm | Boys Basketball - McKeesport @ Penn-Trafford | |
| 3:00pm | Girls Basketball - Plum vs Thomas Jefferson | |
| 3:00pm | Girls Basketball - Trinity vs Chartiers Valley | |
| 3:30pm | Boys Basketball - North Hills vs Chartiers Valley | |
| 3:30pm | Girls Basketball - Armstrong vs Oakland Catholic | |
| 4:00pm | Boys Basketball - Mars vs McNicholas (OH) | |
| 4:00pm | Boys Basketball - Central Catholic vs Malvern Prep | |
| 4:15pm | Boys Basketball - Laurel Highlands vs Allderdice | |
| 4:30pm | Girls Basketball - Seneca Valley vs Moon | |
| 4:30pm | Girls Basketball - Shaler vs Riverview | |
| 4:30pm | Girls Basketball - Mars @ Highlands | |
| 5:00pm | Boys Basketball - Plum vs Redbank Valley | |
| 5:00pm | Girls Basketball - Upper St. Clair vs Southmoreland | |
| 5:00pm | Girls Basketball - Hampton vs Peters Township | |
| 5:00pm | Girls Basketball - McKeesport @ Penn-Trafford | |
| 5:00pm | Girls Basketball - Baldwin vs Obama Academy | |
| 5:30pm | Girls Basketball - Ringgold @ Bentworth | |
| 5:30pm | Girls Basketball - Greensburg Salem vs Charleroi | |
| 6:00pm | Boys Basketball - Norwin vs Seneca Valley | |
| 6:00pm | Boys Basketball - West Mifflin vs Elizabeth Forward | |
| 6:00pm | Boys Basketball - West Allegheny vs Sto-Rox | |
| 6:00pm | Girls Basketball - Bethel Park vs South Fayette | |
| 6:00pm | Girls Basketball - West Allegheny vs Avella | |
| 6:00pm | Girls Basketball - Kiski Area vs Yough | |
| 6:30pm | Boys Basketball - Pine-Richland vs Blackhawk | |
| 6:30pm | Boys Basketball - Hampton vs Grove City | |
| 6:30pm | Girls Basketball - Pine-Richland vs Our Lady of Sacred Heart | |
| 6:30pm | Girls Basketball - Hempfield @ Butler | |
| 6:30pm | Girls Basketball - Connellsville vs West Mifflin | |
| 7:00pm | Boys Basketball - Ringgold @ Charleroi | |
| 7:30pm | Boys Basketball - Moon vs Seton LaSalle | |
| 7:30pm | Boys Basketball - Kiski Area vs Yough | |
| 7:30pm | Boys Basketball - Highlands @ Montour | |
| 7:45pm | Boys Basketball - South Fayette vs Penn Hills | |
| 8:00pm | Boys Basketball - Thomas Jefferson vs Southern Garrett (MD) | |
| 8:00pm | Boys Basketball - New Castle vs Beaver Falls |
# denotes a conference game