Thursday, December 30, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 1:00pm | Girls Basketball - Uniontown vs South Park | |
| 1:30pm | Boys Basketball - Fox Chapel vs Shenango | |
| 1:30pm | Girls Basketball - Mt. Lebanon vs Hoover (OH) | |
| 3:00pm | Boys Basketball - Hempfield vs Connellsville | |
| 3:00pm | Girls Basketball - Fox Chapel @ Shady Side Academy | |
| 3:00pm | Girls Basketball - Indiana vs McLean (VA) | |
| 4:30pm | Boys Basketball - Woodland Hills vs Allderdice | |
| 6:00pm | Boys Basketball - North Allegheny vs Central Florida Christian | |
| 6:00pm | Boys Basketball - Peters Township vs Albert Gallatin | |
| 6:00pm | Girls Basketball - Kiski Area vs Ligonier Valley | |
| 6:30pm | Girls Basketball - Chartiers Valley @ Latrobe | |
| 7:30pm | Boys Basketball - Butler vs Erie City | |
| 7:30pm | Boys Basketball - Canon-McMillan @ Trinity | |
| 7:30pm | Boys Basketball - Armstrong @ Deer Lakes | |
| 7:30pm | Boys Basketball - Kiski Area vs Ligonier Valley | |
| 8:00pm | Boys Basketball - Mt. Lebanon @ Brooke (WV) | |
| 8:15pm | Boys Basketball - Greensburg Salem vs Mt. Pleasant |
# denotes a conference game