Wednesday, March 9, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 6:00pm | Boys Basketball - Fox Chapel vs Cumberland Valley | |
| 6:00pm | Boys Basketball - North Hills vs State College | |
| 6:00pm | Boys Basketball - Mt. Lebanon @ Warwick | |
| 6:00pm | Girls Basketball - South Fayette vs Lampeter Strasburg | |
| 6:00pm | Girls Basketball - Trinity @ Gettysburg | |
| 7:00pm | Boys Basketball - Central Catholic @ Allderdice | |
| 7:00pm | Girls Basketball - Chartiers Valley vs Harbor Creek | |
| 7:00pm | Girls Basketball - McKeesport vs Obama Academy | |
| 7:00pm | Girls Basketball - Moon @ Slippery Rock | |
| 7:00pm | Girls Basketball - Latrobe @ Hollidaysburg | |
| 7:00pm | Girls Basketball - Oakland Catholic @ Warren |
# denotes a conference game