Friday, March 25, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 10:00am | Baseball - Mars vs West Greene | |
| 11:00am | Baseball - Chartiers Valley vs Berks Catholic | |
| 11:00am | Softball - Trinity vs Elmwood (OH) | |
| 12:00pm | Softball - Upper St. Clair vs Burgettstown | |
| 12:15pm | Softball - South Fayette vs Chippewa Falls (WI) | |
| 12:45pm | Baseball - Central Catholic vs Mars | |
| 1:00pm | Softball - Mt. Lebanon @ Moon | |
| 1:00pm | Softball - Trinity vs Bentworth | |
| 1:45pm | Baseball - Baldwin vs Penn Hills | |
| 2:00pm | Baseball - Hempfield vs Blackhawk | |
| 2:00pm | Softball - Mars vs Nutley (NJ) | |
| 3:30pm | Softball - South Fayette vs Masters Academy (FL) | |
| 3:45pm | Softball - Penn Hills @ Oakland Catholic | |
| 4:00pm | Softball - Butler vs New Castle | |
| 4:50pm | Softball - Pine-Richland @ North Catholic | |
| 5:00pm | Baseball - Pine-Richland vs Mt. Lebanon | |
| 5:00pm | Baseball - Seneca Valley @ Fox Chapel | |
| 5:00pm | Baseball - Canon-McMillan @ Bethel Park | |
| 5:00pm | Baseball - Norwin vs Penn-Trafford | |
| 5:00pm | Baseball - McKeesport vs East Allegheny | |
| 5:00pm | Softball - Baldwin vs North Allegheny | |
| 5:00pm | Softball - Bethel Park @ Shaler | |
| 5:00pm | Softball - Hempfield vs Connellsville | |
| 5:00pm | Softball - Plum vs Fox Chapel | |
| 5:00pm | Softball - Penn-Trafford @ Mt. Pleasant | |
| 5:00pm | Softball - Chartiers Valley vs West Mifflin | |
| 5:00pm | Baseball - West Allegheny @ Upper St. Clair | |
| 5:00pm | Softball - Thomas Jefferson @ Frazier | |
| 5:00pm | Softball - Franklin Regional vs Passaic Valley (NJ) | |
| 5:00pm | Softball - Mars vs Masters Academy (FL) | |
| 5:00pm | Softball - North Hills vs Archbishop Wood | |
| 5:15pm | Baseball - Armstrong @ Freeport | |
| 5:15pm | Baseball - Moon @ Central Valley | |
| 5:15pm | Softball - Peters Township @ Keystone Oaks | |
| 5:15pm | Softball - Armstrong @ Freeport | |
| 5:30pm | Baseball - Peters Township vs Brashear | |
| 6:00pm | Girls Basketball - Chartiers Valley vs Cardinal O'Hara | |
| 6:00pm | Baseball - Trinity vs Plymouth-Whitemarsh | |
| 7:00pm | Baseball - North Hills vs Burgettstown | |
| 8:00pm | Softball - Franklin Regional vs Nutley (NJ) | |
| 8:30pm | Boys Basketball - New Castle vs Imhotep Charter | |
| 9:00pm | Baseball - Thomas Jefferson vs Highlands | |
| 9:00pm | Baseball - North Hills vs New Brighton |
# denotes a conference game