Friday, April 1, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 3:30pm | Baseball - Shaler vs Riverview | |
| 4:00pm | Softball - Baldwin vs South Allegheny | |
| 4:00pm | Softball - Canon-McMillan @ Seneca Valley | |
| 4:00pm | Softball - Butler vs Kiski Area | |
| 4:00pm | Softball - Hempfield @ Franklin Regional | |
| 4:00pm | Softball - Norwin @ North Hills | |
| 4:00pm | Softball - Armstrong @ Knoch | |
| 4:00pm | Softball - Woodland Hills vs Carrick | |
| 4:45pm | Baseball - Armstrong vs Indiana | |
| 5:00pm | Baseball - Allderdice @ Peters Township | |
| 5:00pm | Baseball - Upper St. Clair vs Seton LaSalle | |
| 5:00pm | Baseball - Penn-Trafford @ Penn Hills | |
| 5:00pm | Softball - Indiana vs Freeport | |
| 5:00pm | Softball - Shaler @ Highlands | |
| 5:00pm | Softball - West Allegheny @ Montour | |
| 5:00pm | Baseball - Chartiers Valley @ West Mifflin | |
| 5:15pm | Baseball - Mt. Lebanon vs Bethel Park | |
| 5:15pm | Softball - Penn-Trafford vs Bethel Park | |
| 5:30pm | Softball - Peters Township vs Ringgold | |
| 7:00pm | Baseball - Trinity vs Waynesburg |
# denotes a conference game