Wednesday, April 13, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 3:00pm | Baseball - Chartiers Valley vs North Hills # | |
| 4:00pm | Baseball - Gateway vs Penn-Trafford # | |
| 4:00pm | Baseball - Penn-Trafford vs Woodland Hills | |
| 4:00pm | Softball - Woodland Hills @ West Mifflin | |
| 4:30pm | Baseball - Chartiers Valley @ North Hills # | |
| 4:30pm | Softball - Franklin Regional vs Woodland Hills # | |
| 4:45pm | Softball - Armstrong vs Indiana # | |
| 5:00pm | Baseball - Pine-Richland vs Seneca Valley # | |
| 5:00pm | Baseball - Hempfield @ Baldwin # | |
| 5:00pm | Baseball - Mt. Lebanon @ Norwin # | |
| 5:00pm | Baseball - Mars @ Plum # | |
| 5:00pm | Baseball - Connellsville vs Trinity # | |
| 5:00pm | Softball - Hempfield @ Norwin # | |
| 5:00pm | Softball - Penn Hills @ Plum # | |
| 5:00pm | Softball - Albert Gallatin @ Connellsville # | |
| 5:00pm | Softball - Latrobe @ Penn-Trafford # | |
| 5:00pm | Softball - Hampton vs Mars # | |
| 5:00pm | Softball - North Hills @ Shaler # | |
| 5:00pm | Softball - Chartiers Valley vs South Fayette # | |
| 5:00pm | Softball - Mt. Lebanon @ West Mifflin | |
| 5:15pm | Baseball - Moon vs Shaler # | |
| 5:15pm | Softball - Canon-McMillan vs Peters Township # | |
| 6:00pm | Softball - Gateway vs Thomas Jefferson # | |
| 7:00pm | Softball - Butler @ Seneca Valley # | |
| 7:00pm | Softball - North Allegheny vs Pine-Richland # | |
| 7:30pm | Softball - Baldwin vs Bethel Park # | |
| 8:00pm | Baseball - Butler @ Central Catholic # | |
| 8:00pm | Baseball - Peters Township vs Thomas Jefferson # | |
| 8:00pm | Softball - Trinity @ Upper St. Clair # |
# denotes a conference game