Friday, October 14, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 4:30pm | Girls Soccer - Allderdice vs Brashear | |
| 8:00pm | Football - Canon-McMillan @ Upper St. Clair | |
| 8:00pm | Football - Central Catholic @ Penn Hills | |
| 8:00pm | Football - North Allegheny @ Norwin | |
| 8:00pm | Football - Seneca Valley vs North Hills | |
| 8:00pm | Football - Peters Township vs Mt. Lebanon | |
| 8:00pm | Football - Franklin Regional vs Hempfield # | |
| 8:00pm | Football - Gateway @ McKeesport | |
| 8:00pm | Football - Fox Chapel vs Woodland Hills # | |
| 8:00pm | Football - Pine-Richland @ Shaler # | |
| 8:00pm | Football - Baldwin vs South Fayette # | |
| 8:00pm | Football - Bethel Park vs Moon # | |
| 8:30pm | Football - Penn-Trafford vs Plum # |
# denotes a conference game