Friday, September 19, 2025
| Time | Event | Venue/Details |
|---|---|---|
| 7:00pm | Football - Canon-McMillan vs Mt. Lebanon # | |
| 7:00pm | Football - Central Catholic vs Hempfield # | |
| 7:00pm | Football - North Allegheny @ Norwin # | |
| 7:00pm | Football - Seneca Valley @ Moon | |
| 7:00pm | Football - Fox Chapel vs North Hills # | |
| 7:00pm | Football - Penn Hills @ Aliquippa | |
| 7:00pm | Football - Pine-Richland vs Plum # | |
| 7:00pm | Football - Shaler @ Woodland Hills | |
| 7:00pm | Football - Armstrong vs Latrobe # | |
| 7:00pm | Football - Franklin Regional vs Gateway # | |
| 7:00pm | Football - Kiski Area @ Penn-Trafford # | |
| 7:00pm | Football - Baldwin @ Elizabeth Forward | |
| 7:00pm | Football - Bethel Park @ Trinity | |
| 7:00pm | Football - Peters Township vs West Allegheny | |
| 7:00pm | Football - South Fayette vs Belle Vernon | |
| 7:00pm | Football - Upper St. Clair vs McKeesport |
# denotes a conference game