Monday, February 21, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 7:00pm | Boys Basketball - Laurel Highlands vs Woodland Hills | |
| 7:00pm | Boys Basketball - Hampton vs Kiski Area | |
| 7:00pm | Boys Basketball - Penn Hills vs Chartiers Valley | |
| 7:00pm | Boys Basketball - Highlands vs Albert Gallatin | |
| 7:00pm | Boys Basketball - New Castle vs West Mifflin | |
| 7:00pm | Boys Basketball - South Fayette vs Shaler | |
| 8:00pm | Boys Basketball - Mars vs Thomas Jefferson | |
| 8:00pm | Boys Basketball - Gateway vs West Allegheny |
# denotes a conference game