Tuesday, February 22, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 6:00pm | Girls Basketball - Indiana vs Thomas Jefferson | |
| 7:00pm | Girls Basketball - Chartiers Valley vs Connellsville | |
| 7:00pm | Girls Basketball - Moon vs Woodland Hills | |
| 7:00pm | Girls Basketball - Latrobe vs Mars | |
| 7:00pm | Girls Basketball - Trinity vs Armstrong | |
| 7:00pm | Girls Basketball - McKeesport vs Albert Gallatin | |
| 7:00pm | Boys Basketball - North Allegheny vs Baldwin | |
| 7:00pm | Boys Basketball - Mt. Lebanon vs Hempfield | |
| 7:00pm | Boys Basketball - Upper St. Clair vs Penn-Trafford | |
| 7:00pm | Boys Basketball - Pine-Richland vs Bethel Park | |
| 7:00pm | Boys Basketball - Butler vs Norwin | |
| 8:00pm | Girls Basketball - Hampton vs Oakland Catholic | |
| 8:00pm | Girls Basketball - South Fayette vs Greensburg Salem |
# denotes a conference game