Monday, April 4, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 3:30pm | Baseball - Fox Chapel vs Woodland Hills # | |
| 4:00pm | Softball - South Fayette vs Burgettstown | |
| 4:30pm | Softball - Moon vs Trinity # | |
| 4:45pm | Baseball - Armstrong vs Mars # | |
| 4:45pm | Softball - Fox Chapel vs Shaler # | |
| 4:45pm | Softball - Mars vs North Hills # | |
| 5:00pm | Baseball - Allderdice @ Butler # | |
| 5:00pm | Baseball - Central Catholic @ Pine-Richland # | |
| 5:00pm | Baseball - Hempfield @ Upper St. Clair # | |
| 5:00pm | Baseball - Norwin @ Baldwin # | |
| 5:00pm | Baseball - Franklin Regional vs Penn-Trafford # | |
| 5:00pm | Baseball - Latrobe @ McKeesport # | |
| 5:00pm | Baseball - Hampton vs Penn Hills # | |
| 5:00pm | Baseball - Bethel Park @ Trinity # | |
| 5:00pm | Baseball - Connellsville @ Peters Township # | |
| 5:00pm | Softball - Baldwin @ Peters Township # | |
| 5:00pm | Softball - Bethel Park vs Mt. Lebanon # | |
| 5:00pm | Softball - Butler vs Norwin # | |
| 5:00pm | Softball - Hempfield @ Pine-Richland # | |
| 5:00pm | Softball - Armstrong @ Kiski Area # | |
| 5:00pm | Softball - Franklin Regional vs Penn Hills # | |
| 5:00pm | Softball - Indiana vs Punxsutawney | |
| 5:00pm | Softball - Albert Gallatin vs Penn-Trafford # | |
| 5:00pm | Softball - Latrobe @ Thomas Jefferson # | |
| 5:00pm | Softball - Hampton vs Oakland Catholic # | |
| 5:00pm | Softball - Chartiers Valley @ West Allegheny # | |
| 5:15pm | Baseball - Canon-McMillan @ Mt. Lebanon # | |
| 5:15pm | Baseball - Chartiers Valley vs Shaler # | |
| 5:15pm | Baseball - Moon vs South Fayette # | |
| 5:15pm | Baseball - Albert Gallatin vs Thomas Jefferson # | |
| 5:30pm | Baseball - Fox Chapel vs Woodland Hills # | |
| 5:30pm | Baseball - North Hills @ West Allegheny # | |
| 6:00pm | Softball - North Allegheny vs Seneca Valley # | |
| 7:00pm | Baseball - North Allegheny vs Seneca Valley # | |
| 8:00pm | Baseball - Gateway vs Kiski Area # |
# denotes a conference game