Tuesday, April 5, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 4:30pm | Baseball - Allderdice vs Butler # | |
| 4:45pm | Baseball - Central Catholic vs Pine-Richland # | |
| 4:45pm | Baseball - Armstrong @ Mars # | |
| 4:45pm | Softball - Fox Chapel vs Hampton # | |
| 5:00pm | Baseball - North Allegheny @ Seneca Valley # | |
| 5:00pm | Baseball - Canon-McMillan vs Mt. Lebanon # | |
| 5:00pm | Baseball - Norwin vs Baldwin # | |
| 5:00pm | Baseball - Franklin Regional @ Penn-Trafford # | |
| 5:00pm | Baseball - Gateway @ Kiski Area # | |
| 5:00pm | Baseball - Hampton @ Penn Hills # | |
| 5:00pm | Baseball - North Hills vs West Allegheny # | |
| 5:00pm | Baseball - Albert Gallatin @ Thomas Jefferson # | |
| 5:00pm | Baseball - Bethel Park vs Trinity # | |
| 5:00pm | Softball - Bethel Park vs North Allegheny | |
| 5:00pm | Softball - West Allegheny @ Western Beaver # | |
| 5:15pm | Baseball - Hempfield vs Upper St. Clair # | |
| 5:15pm | Baseball - Chartiers Valley @ Shaler # | |
| 5:15pm | Baseball - Moon @ South Fayette # | |
| 8:00pm | Baseball - Latrobe vs McKeesport # |
# denotes a conference game