Friday, April 29, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 4:00pm | Baseball - Woodland Hills vs Carrick | |
| 4:15pm | Baseball - Seneca Valley @ Chartiers Valley | |
| 5:00pm | Baseball - Mt. Lebanon @ Bethel Park | |
| 5:00pm | Baseball - Latrobe @ Laurel Highlands | |
| 5:00pm | Baseball - McKeesport @ West Mifflin | |
| 5:00pm | Baseball - Penn-Trafford vs Plum | |
| 5:00pm | Baseball - Fox Chapel @ Deer Lakes | |
| 5:00pm | Softball - Norwin vs Pine-Richland # | |
| 5:00pm | Softball - Armstrong @ Plum # | |
| 5:00pm | Softball - Franklin Regional vs North Hills | |
| 5:00pm | Softball - Connellsville vs Latrobe # | |
| 5:00pm | Softball - Penn-Trafford vs Thomas Jefferson # | |
| 5:00pm | Softball - Fox Chapel @ Hampton # | |
| 5:00pm | Softball - Mars @ Shaler # | |
| 5:00pm | Softball - Trinity vs West Allegheny # | |
| 5:30pm | Baseball - Thomas Jefferson vs Belle Vernon | |
| 5:30pm | Softball - Peters Township vs Elizabeth Forward | |
| 6:00pm | Softball - Bethel Park @ Canon-McMillan # | |
| 6:00pm | Softball - Kiski Area @ Penn Hills # | |
| 6:00pm | Softball - Albert Gallatin @ Gateway # | |
| 6:00pm | Softball - Kiski Area vs Valley | |
| 7:00pm | Softball - Butler @ North Allegheny # | |
| 7:00pm | Softball - Hempfield @ Seneca Valley # | |
| 8:00pm | Baseball - North Allegheny vs Hampton | |
| 8:00pm | Softball - Chartiers Valley @ Upper St. Clair # | |
| 8:30pm | Baseball - Mars @ Knoch |
# denotes a conference game