Tuesday, April 26, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 3:00pm | Baseball - Fox Chapel vs Belle Vernon | |
| 3:30pm | Baseball - Butler @ North Allegheny # | |
| 4:00pm | Softball - Upper St. Clair @ West Allegheny # | |
| 4:30pm | Baseball - Allderdice vs Pine-Richland # | |
| 4:30pm | Softball - Kiski Area vs Woodland Hills # | |
| 4:45pm | Baseball - Armstrong @ Hampton # | |
| 4:45pm | Baseball - Mars @ Woodland Hills # | |
| 4:45pm | Softball - Armstrong vs Karns City | |
| 5:00pm | Baseball - Central Catholic @ Seneca Valley # | |
| 5:00pm | Baseball - Canon-McMillan vs Hempfield # | |
| 5:00pm | Baseball - Norwin vs Upper St. Clair # | |
| 5:00pm | Baseball - Latrobe @ Kiski Area # | |
| 5:00pm | Baseball - McKeesport @ Penn-Trafford # | |
| 5:00pm | Baseball - Penn Hills vs Plum # | |
| 5:00pm | Baseball - North Hills @ South Fayette # | |
| 5:00pm | Baseball - Shaler vs West Allegheny # | |
| 5:00pm | Baseball - Bethel Park @ Connellsville # | |
| 5:00pm | Softball - Canon-McMillan @ North Allegheny | |
| 5:00pm | Softball - Butler vs Pine-Richland # | |
| 5:00pm | Softball - Trinity vs Western Beaver # | |
| 5:00pm | Softball - Trinity @ Western Beaver # | |
| 5:00pm | Baseball - Kiski Area @ Carrick | |
| 5:15pm | Baseball - Mt. Lebanon vs Baldwin # | |
| 5:15pm | Baseball - Chartiers Valley @ Moon # | |
| 5:30pm | Baseball - Thomas Jefferson vs Trinity # | |
| 8:00pm | Baseball - Franklin Regional @ Gateway # |
# denotes a conference game