Wednesday, April 27, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 4:00pm | Softball - Upper St. Clair vs West Allegheny # | |
| 4:45pm | Softball - Penn Hills vs Woodland Hills # | |
| 5:00pm | Baseball - Kiski Area vs Penn-Trafford # | |
| 5:00pm | Baseball - Albert Gallatin @ Peters Township # | |
| 5:00pm | Softball - Bethel Park vs Peters Township # | |
| 5:00pm | Softball - Butler @ Pine-Richland # | |
| 5:00pm | Softball - Norwin vs Seneca Valley # | |
| 5:00pm | Softball - Franklin Regional vs Indiana # | |
| 5:00pm | Softball - Kiski Area vs Plum # | |
| 5:00pm | Softball - Albert Gallatin @ Thomas Jefferson # | |
| 5:00pm | Softball - Connellsville vs Penn-Trafford # | |
| 5:00pm | Softball - Fox Chapel @ Mars # | |
| 5:00pm | Softball - Hampton @ North Hills # | |
| 5:00pm | Softball - Shaler vs Oakland Catholic # | |
| 5:15pm | Softball - Canon-McMillan @ Mt. Lebanon # | |
| 6:30pm | Softball - Baldwin vs Chartiers Valley | |
| 7:00pm | Softball - Gateway @ Latrobe # |
# denotes a conference game